About Charged multivesicular body protein 6
Charged multivesicular body protein 6 (CHMP6) is a protein
from Homo sapiens identified by UniProt accession
Q96FZ7, 201 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | Charged multivesicular body protein 6 |
|---|
| UniProt accession | Q96FZ7 |
|---|
| Gene | CHMP6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 201 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- HIV infection · score 0.46
- viral disease · score 0.46
- COVID-19 · score 0.37
- severe acute respiratory syndrome · score 0.37
- self reported educational attainment · score 0.06
- sex hormone-binding globulin measurement · score 0.06
- benign neoplasm · score 0.05
- body mass index · score 0.05
- Moyamoya disease · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96FZ7-F1 | alphafold | PREDICTED | 81.92 | — |
Amino-acid sequence (201 residues)
MGNLFGRKKQ SRVTEQDKAI LQLKQQRDKL RQYQKRIAQQ LERERALARQ LLRDGRKERA KLLLKKKRYQ EQLLDRTENQ ISSLEAMVQS IEFTQIEMKV MEGLQFGNEC LNKMHQVMSI EEVERILDET QEAVEYQRQI DELLAGSFTQ EDEDAILEEL SAITQEQIEL PEVPSEPLPE KIPENVPVKA RPRQAELVAA S
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