About Phosphopentomutase
Phosphopentomutase (PGM2) is a protein
from Homo sapiens identified by UniProt accession
Q96G03, 612 residues long.
MolForge cross-references it against 0 known binders and
47 disease associations.
Target properties
| Protein name | Phosphopentomutase |
|---|
| UniProt accession | Q96G03 |
|---|
| Gene | PGM2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 612 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (47)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.32
- lymphocyte percentage of leukocytes · score 0.15
- blood pressure · score 0.12
- endometrial cancer · score 0.09
- hypertension · score 0.09
- lung adenocarcinoma · score 0.08
- neutrophil-to-lymphocyte ratio · score 0.07
- Crohn's disease · score 0.06
- lymphocyte count · score 0.06
- neutrophil percentage of leukocytes · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96G03-F1 | alphafold | PREDICTED | 95.34 | — |
Amino-acid sequence (612 residues)
MAAPEGSGLG EDARLDQETA QWLRWDKNSL TLEAVKRLIA EGNKEELRKC FGARMEFGTA GLRAAMGPGI SRMNDLTIIQ TTQGFCRYLE KQFSDLKQKG IVISFDARAH PSSGGSSRRF ARLAATTFIS QGIPVYLFSD ITPTPFVPFT VSHLKLCAGI MITASHNPKQ DNGYKVYWDN GAQIISPHDK GISQAIEENL EPWPQAWDDS LIDSSPLLHN PSASINNDYF EDLKKYCFHR SVNRETKVKF VHTSVHGVGH SFVQSAFKAF DLVPPEAVPE QKDPDPEFPT VKYPNPEEGK GVLTLSFALA DKTKARIVLA NDPDADRLAV AEKQDSGEWR VFSGNELGAL LGWWLFTSWK EKNQDRSALK DTYMLSSTVS SKILRAIALK EGFHFEETLT GFKWMGNRAK QLIDQGKTVL FAFEEAIGYM CCPFVLDKDG VSAAVISAEL ASFLATKNLS LSQQLKAIYV EYGYHITKAS YFICHDQETI KKLFENLRNY DGKNNYPKAC GKFEISAIRD LTTGYDDSQP DKKAVLPTSK SSQMITFTFA NGGVATMRTS GTEPKIKYYA ELCAPPGNSD PEQLKKELNE LVSAIEEHFF QPQKYNLQPK AD
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