P2Y purinoceptor 11 (P2RY11)

About P2Y purinoceptor 11

P2Y purinoceptor 11 (P2RY11) is a protein from Homo sapiens identified by UniProt accession Q96G91, 374 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	P2Y purinoceptor 11
UniProt accession	Q96G91
Gene	P2RY11
Organism	Homo sapiens
Length	374 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (3)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (6)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.22
narcolepsy-cataplexy syndrome · score 0.16
body height · score 0.06
ICAM-1 measurement · score 0.03
heel bone mineral density · score 0.03
serum gamma-glutamyl transferase measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96G91-F1	alphafold	PREDICTED	80.71	—

Amino-acid sequence (374 residues)

MAANVSGAKS CPANFLAAAD DKLSGFQGDF LWPILVVEFL VAVASNGLAL YRFSIRKQRP WHPAVVFSVQ LAVSDLLCAL TLPPLAAYLY PPKHWRYGEA ACRLERFLFT CNLLGSVIFI TCISLNRYLG IVHPFFARSH LRPKHAWAVS AAGWVLAALL AMPTLSFSHL KRPQQGAGNC SVARPEACIK CLGTADHGLA AYRAYSLVLA GLGCGLPLLL TLAAYGALGR AVLRSPGMTV AEKLRVAALV ASGVALYASS YVPYHIMRVL NVDARRRWST RCPSFADIAQ ATAALELGPY VGYQVMRGLM PLAFCVHPLL YMAAVPSLGC CCRHCPGYRD SWNPEDAKST GQALPLNATA APKPSEPQSR ELSQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards