About Protein LTV1 homolog
Protein LTV1 homolog (LTV1) is a protein
from Homo sapiens identified by UniProt accession
Q96GA3, 475 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Protein LTV1 homolog |
|---|
| UniProt accession | Q96GA3 |
|---|
| Gene | LTV1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 475 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- inflammatory poikiloderma with hair abnormalities and acral keratoses · score 0.48
- lysosomal storage disease · score 0.46
- Parkinson disease · score 0.46
- multiple sclerosis · score 0.46
- Alzheimer disease · score 0.46
- transient myeloproliferative syndrome · score 0.05
- pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 9 · score 0.04
- sitting height measurement · score 0.04
- vital capacity · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96GA3-F1 | alphafold | PREDICTED | 68.67 | — |
Amino-acid sequence (475 residues)
MPHRKKKPFI EKKKAVSFHL VHRSQRDPLA ADESAPQRVL LPTQKIDNEE RRAEQRKYGV FFDDDYDYLQ HLKEPSGPSE LIPSSTFSAH NRREEKEETL VIPSTGIKLP SSVFASEFEE DVGLLNKAAP VSGPRLDFDP DIVAALDDDF DFDDPDNLLE DDFILQANKA TGEEEGMDIQ KSENEDDSEW EDVDDEKGDS NDDYDSAGLL SDEDCMSVPG KTHRAIADHL FWSEETKSRF TEYSMTSSVM RRNEQLTLHD ERFEKFYEQY DDDEIGALDN AELEGSIQVD SNRLQEVLND YYKEKAENCV KLNTLEPLED QDLPMNELDE SEEEEMITVV LEEAKEKWDC ESICSTYSNL YNHPQLIKYQ PKPKQIRISS KTGIPLNVLP KKGLTAKQTE RIQMINGSDL PKVSTQPRSK NESKEDKRAR KQAIKEERKE RRVEKKANKL AFKLEKRRQE KELLNLKKNV EGLKL
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