Serine dehydratase-like (SDSL)

About Serine dehydratase-like

Serine dehydratase-like (SDSL) is a protein from Homo sapiens identified by UniProt accession Q96GA7, 329 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	Serine dehydratase-like
UniProt accession	Q96GA7
Gene	SDSL
Organism	Homo sapiens
Length	329 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (44)

Diseases linked to this target (Open Targets).

body mass index · score 0.13
diabetic ketoacidosis · score 0.12
smoking behavior · score 0.08
cerebrospinal fluid biomarker measurement · score 0.06
blood protein measurement · score 0.06
melorheostosis · score 0.04
dacryocystitis-osteopoikilosis syndrome · score 0.04
self reported educational attainment · score 0.04
mathematical ability · score 0.04
autosomal recessive hypophosphatemic rickets · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96GA7-F1	alphafold	PREDICTED	95.20	—

Amino-acid sequence (329 residues)

MDGPVAEHAK QEPFHVVTPL LESWALSQVA GMPVFLKCEN VQPSGSFKIR GIGHFCQEMA KKGCRHLVCS SGGNAGIAAA YAARKLGIPA TIVLPESTSL QVVQRLQGEG AEVQLTGKVW DEANLRAQEL AKRDGWENVP PFDHPLIWKG HASLVQELKA VLRTPPGALV LAVGGGGLLA GVVAGLLEVG WQHVPIIAME THGAHCFNAA ITAGKLVTLP DITSVAKSLG AKTVAARALE CMQVCKIHSE VVEDTEAVSA VQQLLDDERM LVEPACGAAL AAIYSGLLRR LQAEGCLPPS LTSVVVIVCG GNNINSRELQ ALKTHLGQV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards