About Large ribosomal subunit protein mL48
Large ribosomal subunit protein mL48 (MRPL48) is a protein
from Homo sapiens identified by UniProt accession
Q96GC5, 212 residues long.
MolForge cross-references it against 0 known binders and
19 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein mL48 |
|---|
| UniProt accession | Q96GC5 |
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| Gene | MRPL48 |
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| Organism | Homo sapiens |
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| Length | 212 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (19)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- brain measurement · score 0.08
- cortical thickness · score 0.08
- hepatocellular carcinoma · score 0.07
- insomnia measurement · score 0.06
- metabolite measurement · score 0.05
- neoplasm · score 0.05
- blood protein measurement · score 0.04
- cancer · score 0.02
- non-alcoholic steatohepatitis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96GC5-F1 | alphafold | PREDICTED | 76.29 | — |
Amino-acid sequence (212 residues)
MSGTLEKVLC LRNNTIFKQA FSLLRFRTSG EKPIYSVGGI LLSISRPYKT KPTHGIGKYK HLIKAEEPKK KKGKVEVRAI NLGTDYEYGV LNIHLTAYDM TLAESYAQYV HNLCNSLSIK VEESYAMPTK TIEVLQLQDQ GSKMLLDSVL TTHERVVQIS GLSATFAEIF LEIIQSSLPE GVRLSVKEHT EEDFKGRFKA RPELEELLAK LK
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