Vacuole membrane protein 1 (VMP1)

About Vacuole membrane protein 1

Vacuole membrane protein 1 (VMP1) is a protein from Homo sapiens identified by UniProt accession Q96GC9, 406 residues long. MolForge cross-references it against 0 known binders and 159 disease associations.

Target properties

Protein name	Vacuole membrane protein 1
UniProt accession	Q96GC9
Gene	VMP1
Organism	Homo sapiens
Length	406 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (159)

Diseases linked to this target (Open Targets).

neutrophil count · score 0.44
leukocyte count · score 0.43
neurodegenerative disease · score 0.42
hematocrit · score 0.41
basophil count · score 0.41
triglyceride measurement · score 0.39
monocyte count · score 0.38
hemoglobin measurement · score 0.38
multiple sclerosis · score 0.37
platelet crit · score 0.36

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96GC9-F1	alphafold	PREDICTED	78.39	—

Amino-acid sequence (406 residues)

MAENGKNCDQ RRVAMNKEHH NGNFTDPSSV NEKKRREREE RQNIVLWRQP LITLQYFSLE ILVILKEWTS KLWHRQSIVV SFLLLLAVLI ATYYVEGVHQ QYVQRIEKQF LLYAYWIGLG ILSSVGLGTG LHTFLLYLGP HIASVTLAAY ECNSVNFPEP PYPDQIICPD EEGTEGTISL WSIISKVRIE ACMWGIGTAI GELPPYFMAR AARLSGAEPD DEEYQEFEEM LEHAESAQDF ASRAKLAVQK LVQKVGFFGI LACASIPNPL FDLAGITCGH FLVPFWTFFG ATLIGKAIIK MHIQKIFVII TFSKHIVEQM VAFIGAVPGI GPSLQKPFQE YLEAQRQKLH HKSEMGTPQG ENWLSWMFEK LVVVMVCYFI LSIINSMAQS YAKRIQQRLN SEEKTK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards