About Chronophin
Chronophin (PDXP) is a protein
from Homo sapiens identified by UniProt accession
Q96GD0, 296 residues long.
MolForge cross-references it against 0 known binders and
75 disease associations.
Target properties
| Protein name | Chronophin |
|---|
| UniProt accession | Q96GD0 |
|---|
| Gene | PDXP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 296 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (75)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.21
- myeloid white cell count · score 0.06
- leukocyte count · score 0.06
- cancer · score 0.04
- Spinal cord injury · score 0.04
- neoplasm · score 0.04
- glioblastoma multiforme · score 0.03
- attention deficit hyperactivity disorder · score 0.03
- glioblastoma · score 0.02
- glioma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96GD0-F1 | alphafold | PREDICTED | 95.79 | — |
Amino-acid sequence (296 residues)
MARCERLRGA ALRDVLGRAQ GVLFDCDGVL WNGERAVPGA PELLERLARA GKAALFVSNN SRRARPELAL RFARLGFGGL RAEQLFSSAL CAARLLRQRL PGPPDAPGAV FVLGGEGLRA ELRAAGLRLA GDPSAGDGAA PRVRAVLVGY DEHFSFAKLR EACAHLRDPE CLLVATDRDP WHPLSDGSRT PGTGSLAAAV ETASGRQALV VGKPSPYMFE CITENFSIDP ARTLMVGDRL ETDILFGHRC GMTTVLTLTG VSRLEEAQAY LAAGQHDLVP HYYVESIADL TEGLED
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