About Protein FAM163A
Protein FAM163A (FAM163A) is a protein
from Homo sapiens identified by UniProt accession
Q96GL9, 167 residues long.
MolForge cross-references it against 0 known binders and
39 disease associations.
Target properties
| Protein name | Protein FAM163A |
|---|
| UniProt accession | Q96GL9 |
|---|
| Gene | FAM163A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 167 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (39)
Diseases linked to this target (Open Targets).
- Abruptio Placentae · score 0.30
- smoking behavior · score 0.21
- monocyte percentage of leukocytes · score 0.05
- MODY · score 0.04
- diabetes mellitus, permanent neonatal 4 · score 0.04
- permanent neonatal diabetes mellitus 1 · score 0.04
- hemoglobin E-beta-thalassemia syndrome · score 0.04
- hemoglobin D disease · score 0.04
- diabetes mellitus, transient neonatal, 3 · score 0.04
- Hemolytic anemia due to red cell pyruvate kinase deficiency · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96GL9-F1 | alphafold | PREDICTED | 58.65 | — |
Amino-acid sequence (167 residues)
MTAGTVVITG GILATVILLC IIAVLCYCRL QYYCCKKSGT EVADEEEERE HDLPTHPRGP TCNACSSQAL DGRGSLAPLT SEPCSQPCGV AASHCTTCSP YSSPFYIRTA DMVPNGGGGE RLSFAPTYYK EGGPPSLKLA APQSYPVTWP GSGREAFTNP RAISTDV
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