About Scavenger receptor class F member 2
Scavenger receptor class F member 2 (SCARF2) is a protein
from Homo sapiens identified by UniProt accession
Q96GP6, 871 residues long.
MolForge cross-references it against 0 known binders and
71 disease associations.
Target properties
| Protein name | Scavenger receptor class F member 2 |
|---|
| UniProt accession | Q96GP6 |
|---|
| Gene | SCARF2 |
|---|
| Organism | Homo sapiens |
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| Length | 871 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (71)
Diseases linked to this target (Open Targets).
- van den Ende-Gupta syndrome · score 0.77
- body height · score 0.43
- FEV/FVC ratio · score 0.42
- refractive error measurement · score 0.41
- appendicular lean mass · score 0.38
- forced expiratory volume · score 0.36
- brain measurement · score 0.28
- type 2 diabetes mellitus · score 0.28
- neurodegenerative disease · score 0.27
- balding measurement · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96GP6-F1 | alphafold | PREDICTED | 64.54 | — |
Amino-acid sequence (871 residues)
MEGAGPRGAG PARRRGAGGP PSPLLPSLLL LLLLWMLPDT VAPQELNPRG RNVCRAPGSQ VPTCCAGWRQ QGDECGIAVC EGNSTCSENE VCVRPGECRC RHGYFGANCD TKCPRQFWGP DCKELCSCHP HGQCEDVTGQ CTCHARRWGA RCEHACQCQH GTCHPRSGAC RCEPGWWGAQ CASACYCSAT SRCDPQTGAC LCHAGWWGRS CNNQCACNSS PCEQQSGRCQ CRERTFGARC DRYCQCFRGR CHPVDGTCAC EPGYRGKYCR EPCPAGFYGL GCRRRCGQCK GQQPCTVAEG RCLTCEPGWN GTKCDQPCAT GFYGEGCSHR CPPCRDGHAC NHVTGKCTRC NAGWIGDRCE TKCSNGTYGE DCAFVCADCG SGHCDFQSGR CLCSPGVHGP HCNVTCPPGL HGADCAQACS CHEDTCDPVT GACHLETNQR KGVMGAGALL VLLVCLLLSL LGCCCACRGK DPTRRPRPRR ELSLGRKKAP HRLCGRFSRI SMKLPRIPLR RQKLPKVVVA HHDLDNTLNC SFLEPPSGLE QPSPSWSSRA SFSSFDTTDE GPVYCVPHEE APAESRDPEV PTVPAEAPAP SPVPLTTPAS AEEAIPLPAS SDSERSASSV EGPGGALYAR VARREARPAR ARGEIGGLSL SPSPERRKPP PPDPATKPKV SWIHGKHSAA AAGRAPSPPP PGSEAAPSPS KRKRTPSDKS AHTVEHGSPR TRDPTPRPPG LPEEATALAA PSPPRARARG RGPGLLEPTD AGGPPRSAPE AASMLAAELR GKTRSLGRAE VALGAQGPRE KPAPPQKAKR SVPPASPARA PPATETPGPE KAATDLPAPE TPRKKTPIQK PPRKKSREAA GELGRAGAPT L
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