BLOC-1-related complex subunit 6 (BORCS6)

About BLOC-1-related complex subunit 6

BLOC-1-related complex subunit 6 (BORCS6) is a protein from Homo sapiens identified by UniProt accession Q96GS4, 357 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	BLOC-1-related complex subunit 6
UniProt accession	Q96GS4
Gene	BORCS6
Organism	Homo sapiens
Length	357 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

Fraser syndrome · score 0.11
memory impairment · score 0.09
alcohol drinking · score 0.09
apolipoprotein A 1 measurement · score 0.08
high density lipoprotein cholesterol measurement · score 0.05
hypoparathyroidism, familial isolated, 2 · score 0.04
potassium measurement · score 0.04
Primary hypomagnesemia with secondary hypocalcemia · score 0.04
familial isolated hyperparathyroidism · score 0.04
hyperparathyroidism · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96GS4-F1	alphafold	PREDICTED	65.39	—

Amino-acid sequence (357 residues)

MESSRGRPGP ETDLLAVAEH QALVFGGGPG RTSSEPPAGL RVSGEEETEN VGGANRHPRT SPKTSSCGVV HRPEREALEN EPGPQGTLSG AGSRRGAPGA EHEPSLSSRH KNPAPPEGKP SSGRDCRRGG PGGGMDVEQQ EEEDNDEEAA AGSRAGRSFS SRLQDSRSLD GLSEACGGAG SSGSAESGAG GGRRATISSP LELEGTVSRH GDLTHFVANN LQLKIRLSGA PPPPPSAPAR PCPAPAPTPT PAIPPIDPEV LRDLERLSRE LGGRVDRLLR GLGGAVQELT ALSVGCIQTY RDAVDSLGEA VDMSIKGMYT LLARCEELER ALQPVQGLAR QVRDIRRTLE VLEALCK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards