About Macrophage immunometabolism regulator
Macrophage immunometabolism regulator (MACIR) is a protein
from Homo sapiens identified by UniProt accession
Q96GV9, 206 residues long.
MolForge cross-references it against 0 known binders and
79 disease associations.
Target properties
| Protein name | Macrophage immunometabolism regulator |
|---|
| UniProt accession | Q96GV9 |
|---|
| Gene | MACIR |
|---|
| Organism | Homo sapiens |
|---|
| Length | 206 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (79)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.37
- erythrocyte count · score 0.36
- mean corpuscular hemoglobin · score 0.35
- rheumatoid arthritis · score 0.34
- hypothyroidism · score 0.33
- mean corpuscular hemoglobin concentration · score 0.33
- red blood cell density measurement · score 0.31
- mean reticulocyte volume · score 0.30
- risk-taking behaviour · score 0.30
- Thyroid preparation use measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96GV9-F1 | alphafold | PREDICTED | 57.34 | — |
Amino-acid sequence (206 residues)
MEVDINGESR STLTTLPFPG AEANSPGKAE AEKPRCSSTP CSPMRRTVSG YQILHMDSNY LVGFTTGEEL LKLAQKCTGG EESKAEAMPS LRSKQLDAGL ARSSRLYKTR SRYYQPYEIP AVNGRRRRRM PSSGDKCTKS LPYEPYKALH GPLPLCLLKG KRAHSKSLDY LNLDKMIKEP ADTEVLQYQL QHLTLRGDRV FARNNT
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