Ataxin-7-like protein 3B (ATXN7L3B)

About Ataxin-7-like protein 3B

Ataxin-7-like protein 3B (ATXN7L3B) is a protein from Homo sapiens identified by UniProt accession Q96GX2, 97 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

Target properties

Protein name	Ataxin-7-like protein 3B
UniProt accession	Q96GX2
Gene	ATXN7L3B
Organism	Homo sapiens
Length	97 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (18)

Diseases linked to this target (Open Targets).

self reported educational attainment · score 0.31
cigarettes per day measurement · score 0.21
smoking cessation · score 0.20
ulcerative colitis · score 0.17
depressive symptom measurement · score 0.16
schizophrenia · score 0.16
adolescent idiopathic scoliosis · score 0.16
urate measurement · score 0.16
heel bone mineral density · score 0.16
type 1 diabetes mellitus · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96GX2-F1	alphafold	PREDICTED	67.37	—

Amino-acid sequence (97 residues)

MEEISLANLD TNKLEAIAQE IYVDLIEDSC LGFCFEVHRA VKCGYFYLEF AETGSVKDFG IQPVEDKGAC RLPLCSLPGE PGNGPDQQLQ RSPPEFQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards