Zinc finger C2HC domain-containing protein 1A…

About Zinc finger C2HC domain-containing protein 1A

Zinc finger C2HC domain-containing protein 1A (ZC2HC1A) is a protein from Homo sapiens identified by UniProt accession Q96GY0, 325 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.

Target properties

Protein name	Zinc finger C2HC domain-containing protein 1A
UniProt accession	Q96GY0
Gene	ZC2HC1A
Organism	Homo sapiens
Length	325 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (34)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.45
leukocyte count · score 0.39
neutrophil percentage of leukocytes · score 0.35
lymphocyte percentage of leukocytes · score 0.34
psoriasis · score 0.33
multiple sclerosis · score 0.28
platelet-to-lymphocyte ratio · score 0.27
monocyte percentage of leukocytes · score 0.26
myeloid white cell count · score 0.26
lymphocyte:monocyte ratio · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96GY0-F1	alphafold	PREDICTED	64.06	—

Amino-acid sequence (325 residues)

MEGLEENGGV VQVGELLPCK ICGRTFFPVA LKKHGPICQK TATKKRKTFD SSRQRAEGTD IPTVKPLKPR PEPPKKPSNW RRKHEEFIAT IRAAKGLDQA LKEGGKLPPP PPPSYDPDYI QCPYCQRRFN ENAADRHINF CKEQAARISN KGKFSTDTKG KPTSRTQVYK PPALKKSNSP GTASSGSSRL PQPSGAGKTV VGVPSGKVSS SSSSLGNKLQ TLSPSHKGIA APHAGANVKP RNSTPPSLAR NPAPGVLTNK RKTYTESYIA RPDGDCASSL NGGNIKGIEG HSPGNLPKFC HECGTKYPVE WAKFCCECGI RRMIL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Zinc finger C2HC domain-containing protein 1A (ZC2HC1A)