Protein lin-37 homolog (LIN37)

Homo sapiens — UniProt Q96GY3

Gene: LIN37Homo sapiensSwissProt reviewed

About Protein lin-37 homolog

Protein lin-37 homolog (LIN37) is a protein from Homo sapiens identified by UniProt accession Q96GY3, 246 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

Target properties

Protein nameProtein lin-37 homolog
UniProt accessionQ96GY3
GeneLIN37
OrganismHomo sapiens
Length246 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (18)

Diseases linked to this target (Open Targets).

  • blood protein measurement · score 0.18
  • Red cell distribution width · score 0.17
  • mathematical ability · score 0.05
  • white matter microstructure measurement · score 0.05
  • self reported educational attainment · score 0.03
  • age at first sexual intercourse measurement · score 0.03
  • eosinophil percentage of leukocytes · score 0.03
  • cortical thickness · score 0.02
  • body height · score 0.02
  • neuroimaging measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96GY3-F1alphafoldPREDICTED69.86—

Amino-acid sequence (246 residues)

MFPVKVKVEK SELEMAKARN QLDAVLQCLL EKSHMDRERL DEEAGKTPSD THNKDCSIAA TGKRPSARFP HQRRKKRREM DDGLAEGGPQ RSNTYVIKLF DRSVDLAQFS ENTPLYPICR AWMRNSPSVR ERECSPSSPL PPLPEDEEGS EVTNSKSRDV YKLPPPTPPG PPGDACRSRI PSPLQPEMQG TPDDEPSEPE PSPSTLIYRN MQRWKRIRQR WKEASHRNQL RYSESMKILR EMYERQ

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Quick facts

UniProtQ96GY3
GeneLIN37
OrganismHomo sapiens
Length246
Binders0
Diseases18
View on UniProt