Myb/SANT-like DNA-binding domain-containing protein…

About Myb/SANT-like DNA-binding domain-containing protein 3

Myb/SANT-like DNA-binding domain-containing protein 3 (MSANTD3) is a protein from Homo sapiens identified by UniProt accession Q96H12, 275 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	Myb/SANT-like DNA-binding domain-containing protein 3
UniProt accession	Q96H12
Gene	MSANTD3
Organism	Homo sapiens
Length	275 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.33
medical procedure · score 0.11
acinar cell carcinoma · score 0.06
deafness · score 0.05
forced expiratory volume · score 0.04
creatinine clearance measurement · score 0.03
pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 9 · score 0.03
lean body mass · score 0.02
body height · score 0.02
Salivary Gland Acinic Cell Carcinoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96H12-F1	alphafold	PREDICTED	74.02	—

Amino-acid sequence (275 residues)

MQNNEIIKPA KYFSELEKSI LLALVEKYKY VLECKKSDAR TIALKQRTWQ ALAHEYNSQP SVSLRDFKQL KKCWENIKAR TKKIMAHERR EKVKRSVSPL LSTHVLGKEK IASMLPEQLY FLQSPPEEEP EYHPDASAQE SFAVSNRELC DDEKEFIHFP VCEGTSQPEP SCSAVRITAN KNYRSKTSQE GALKKMHEEE HHQQMSILQL QLIQMNEVHV AKIQQIEREC EMAEEEHRIK MEVLNKKKMY WERKLQTFTK EWPVSSFNRP FPNSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Myb/SANT-like DNA-binding domain-containing protein 3 (MSANTD3)