About T-cell immunoglobulin and mucin domain-containing protein 4
T-cell immunoglobulin and mucin domain-containing protein 4 (TIMD4) is a protein
from Homo sapiens identified by UniProt accession
Q96H15, 378 residues long.
MolForge cross-references it against 0 known binders and
256 disease associations.
Target properties
| Protein name | T-cell immunoglobulin and mucin domain-containing protein 4 |
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| UniProt accession | Q96H15 |
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| Gene | TIMD4 |
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| Organism | Homo sapiens |
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| Length | 378 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (256)
Diseases linked to this target (Open Targets).
- total cholesterol measurement · score 0.51
- low density lipoprotein cholesterol measurement · score 0.44
- triglyceride measurement · score 0.44
- kidney injury molecule 1 measurement · score 0.43
- apolipoprotein B measurement · score 0.42
- platelet count · score 0.40
- platelet crit · score 0.35
- HMG CoA reductase inhibitor use measurement · score 0.34
- mean corpuscular volume · score 0.34
- lymphocyte count · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96H15-F1 | alphafold | PREDICTED | 63.43 | — |
Amino-acid sequence (378 residues)
MSKEPLILWL MIEFWWLYLT PVTSETVVTE VLGHRVTLPC LYSSWSHNSN SMCWGKDQCP YSGCKEALIR TDGMRVTSRK SAKYRLQGTI PRGDVSLTIL NPSESDSGVY CCRIEVPGWF NDVKINVRLN LQRASTTTHR TATTTTRRTT TTSPTTTRQM TTTPAALPTT VVTTPDLTTG TPLQMTTIAV FTTANTCLSL TPSTLPEEAT GLLTPEPSKE GPILTAESET VLPSDSWSSV ESTSADTVLL TSKESKVWDL PSTSHVSMWK TSDSVSSPQP GASDTAVPEQ NKTTKTGQMD GIPMSMKNEM PISQLLMIIA PSLGFVLFAL FVAFLLRGKL METYCSQKHT RLDYIGDSKN VLNDVQHGRE DEDGLFTL
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