About Vacuolar-sorting protein SNF8
Vacuolar-sorting protein SNF8 (SNF8) is a protein
from Homo sapiens identified by UniProt accession
Q96H20, 258 residues long.
MolForge cross-references it against 0 known binders and
64 disease associations.
Target properties
| Protein name | Vacuolar-sorting protein SNF8 |
|---|
| UniProt accession | Q96H20 |
|---|
| Gene | SNF8 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 258 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (64)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- viral disease · score 0.46
- Neurodevelopmental disorder · score 0.25
- systolic blood pressure · score 0.22
- type 2 diabetes mellitus · score 0.20
- body height · score 0.20
- self reported educational attainment · score 0.20
- epilepsy · score 0.18
- Optic atrophy · score 0.18
- Intellectual disability · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96H20-F1 | alphafold | PREDICTED | 84.92 | — |
Amino-acid sequence (258 residues)
MHRRGVGAGA IAKKKLAEAK YKERGTVLAE DQLAQMSKQL DMFKTNLEEF ASKHKQEIRK NPEFRVQFQD MCATIGVDPL ASGKGFWSEM LGVGDFYYEL GVQIIEVCLA LKHRNGGLIT LEELHQQVLK GRGKFAQDVS QDDLIRAIKK LKALGTGFGI IPVGGTYLIQ SVPAELNMDH TVVLQLAEKN GYVTVSEIKA SLKWETERAR QVLEHLLKEG LAWLDLQAPG EAHYWLPALF TDLYSQEITA EEAREALP
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