Probable RNA-binding protein 18 (RBM18)

About Probable RNA-binding protein 18

Probable RNA-binding protein 18 (RBM18) is a protein from Homo sapiens identified by UniProt accession Q96H35, 190 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Probable RNA-binding protein 18
UniProt accession	Q96H35
Gene	RBM18
Organism	Homo sapiens
Length	190 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.46
body mass index · score 0.02
heel bone mineral density · score 0.02
Åland Islands eye disease · score 0.00
benign prostatic hyperplasia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96H35-F1	alphafold	PREDICTED	74.21	—

Amino-acid sequence (190 residues)

MEAETKTLPL ENASILSEGS LQEGHRLWIG NLDPKITEYH LLKLLQKFGK VKQFDFLFHK SGALEGQPRG YCFVNFETKQ EAEQAIQCLN GKLALSKKLV VRWAHAQVKR YDHNKNDKIL PISLEPSSST EPTQSNLSVT AKIKAIEAKL KMMAENPDAE YPAAPVYSYF KPPDKKRTTP YSRTAWKSRR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards