About Unconventional myosin-XIX
Unconventional myosin-XIX (MYO19) is a protein
from Homo sapiens identified by UniProt accession
Q96H55, 970 residues long.
MolForge cross-references it against 0 known binders and
55 disease associations.
Target properties
| Protein name | Unconventional myosin-XIX |
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| UniProt accession | Q96H55 |
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| Gene | MYO19 |
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| Organism | Homo sapiens |
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| Length | 970 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (55)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- macrophage inflammatory protein 1b measurement · score 0.28
- body mass index · score 0.18
- body fat percentage · score 0.16
- body weight · score 0.16
- lean body mass · score 0.15
- Red cell distribution width · score 0.14
- fat body mass · score 0.14
- mathematical ability · score 0.11
- glomerular filtration rate · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96H55-F1 | alphafold | PREDICTED | 76.42 | — |
Amino-acid sequence (970 residues)
MLQQVNGHNP GSDGQAREYL REDLQEFLGG EVLLYKLDDL TRVNPVTLET VLRCLQARYM ADTFYTNAGC TLVALNPFKP VPQLYSPELM REYHAAPQPQ KLKPHVFTVG EQTYRNVKSL IEPVNQSIVV SGESGAGKTW TSRCLMKFYA VVATSPASWE SHKIAERIEQ RILNSNPVME AFGNACTLRN NNSSRFGKFI QLQLNRAQQM TGAAVQTYLL EKTRVACQAS SERNFHIFYQ ICKGASEDER LQWHLPEGAA FSWLPNPERS LEEDCFEVTR EAMLHLGIDT PTQNNIFKVL AGLLHLGNIQ FAASEDEAQP CQPMDDAKYS VRTAASLLGL PEDVLLEMVQ IRTIRAGRQQ QVFRKPCARA ECDTRRDCLA KLIYARLFDW LVSVINSSIC ADTDSWTTFI GLLDVYGFES FPDNSLEQLC INYANEKLQQ HFVAHYLRAQ QEEYAVEGLE WSFINYQDNQ PCLDLIEGSP ISICSLINEE CRLNRPSSAA QLQTRIETAL AGSPCLGHNK LSREPSFIVV HYAGPVRYHT AGLVEKNKDP IPPELTRLLQ QSQDPLLMGL FPTNPKEKTQ EEPPGQSRAP VLTVVSKFKA SLEQLLQVLH STTPHYIRCI KPNSQGQAQT FLQEEVLSQL EACGLVETIH ISAAGFPIRV SHRNFVERYK LLRRLHPCTS SGPDSPYPAK GLPEWCPHSE EATLEPLIQD ILHTLPVLTQ AAAITGDSAE AMPAPMHCGR TKVFMTDSML ELLECGRARV LEQCARCIQG GWRRHRHREQ ERQWRAVMLI QAAIRSWLTR KHIQRLHAAA TVIKRAWQKW RIRMACLAAK ELDGVEEKHF SQAPCSLSTS PLQTRLLEAI IRLWPLGLVL ANTAMGVGSF QRKLVVWACL QLPRGSPSSY TVQTAQDQAG VTSIRALPQG SIKFHCRKSP LRYADICPEP SPYSITGFNQ ILLERHRLIH VTSSAFTGLG
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