About Solute carrier family 25 member 44
Solute carrier family 25 member 44 (SLC25A44) is a protein
from Homo sapiens identified by UniProt accession
Q96H78, 314 residues long.
MolForge cross-references it against 0 known binders and
61 disease associations.
Target properties
| Protein name | Solute carrier family 25 member 44 |
| UniProt accession | Q96H78 |
| Gene | SLC25A44 |
| Organism | Homo sapiens |
| Length | 314 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- Testicular Germ Cell Tumor · score 0.11
- attention deficit hyperactivity disorder · score 0.09
- testicular carcinoma · score 0.09
- C-reactive protein measurement · score 0.08
- cystatin C measurement · score 0.08
- mosaic loss of chromosome Y measurement · score 0.07
- monocyte count · score 0.07
- attention deficit-hyperactivity disorder 8 · score 0.06
- schizophrenia 15 · score 0.06
- serum urea measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q96H78-F1 | alphafold | PREDICTED | 80.98 | — |
Amino-acid sequence (314 residues)
MEDKRNIQII EWEHLDKKKF YVFGVAMTMM IRVSVYPFTL IRTRLQVQKG KSLYHGTFDA FIKILRADGI TGLYRGFLVN TFTLISGQCY VTTYELTRKF VADYSQSNTV KSLVAGGSAS LVAQSITVPI DVVSQHLMMQ RKGEKMGRFQ VRGNPEGQGV VAFGQTKDII RQILQADGLR GFYRGYVASL LTYIPNSAVW WPFYHFYAEQ LSYLCPKECP HIVFQAVSGP LAAATASILT NPMDVIRTRV QVEGKNSIIL TFRQLMAEEG PWGLMKGLSA RIISATPSTI VIVVGYESLK KLSLRPELVD SRHW
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