Uncharacterized protein C1orf159 (C1orf159)

About Uncharacterized protein C1orf159

Uncharacterized protein C1orf159 (C1orf159) is a protein from Homo sapiens identified by UniProt accession Q96HA4, 380 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	Uncharacterized protein C1orf159
UniProt accession	Q96HA4
Gene	C1orf159
Organism	Homo sapiens
Length	380 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.31
blood phosphate measurement · score 0.25
calcium measurement · score 0.10
blood protein measurement · score 0.04
combined immunodeficiency with skin granulomas · score 0.04
neutropenia, severe congenital, 2, autosomal dominant · score 0.04
urate measurement · score 0.04
body height · score 0.04
severe combined immunodeficiency due to IKK2 deficiency · score 0.03
X-Linked Combined Immunodeficiency Diseases · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96HA4-F1	alphafold	PREDICTED	49.18	—

Amino-acid sequence (380 residues)

MALRHLALLA GLLVGVASKS MENTVTRNST AVINTQAEGT LSPPGLSSLP VVREWALTHT AQLPECCVDV VGVNASCPGA SLCGPGCYRR WNADGSASCV RCGNGTLPAY NGSECRSFAG PGAPFPMNRS SGTPGRPHPG APRVAASLFL GTFFISSGLI LSVAGFFYLK RSSKLPRACY RRNKAPALQP GEAAAMIPPP QSSGNSSCRI PLWGFPSLGQ SQGALWVCPQ TGLPGSGSRP PLPGSPGDPP TRQGQGRIWL VPPALDLSWI WPAPPARPPL IPVTSMLFPV PETWGLQERR THHDRADPQY LLLLEVQLHP RTDAAGLRQA LLSSHRFSGA GSGGPKSQPV RKPRYVRRER PLDRATDPAA FPGEARISNV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards