Protein N-terminal glutamine amidohydrolase (NTAQ1)

About Protein N-terminal glutamine amidohydrolase

Protein N-terminal glutamine amidohydrolase (NTAQ1) is a protein from Homo sapiens identified by UniProt accession Q96HA8, 205 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

Target properties

Protein name	Protein N-terminal glutamine amidohydrolase
UniProt accession	Q96HA8
Gene	NTAQ1
Organism	Homo sapiens
Length	205 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (32)

Diseases linked to this target (Open Targets).

appendicular lean mass · score 0.14
body height · score 0.13
hemoglobin D disease · score 0.05
hemoglobin E-beta-thalassemia syndrome · score 0.05
dehydrated hereditary stomatocytosis · score 0.04
hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.04
dominant beta-thalassemia · score 0.04
hemoglobin E disease · score 0.04
Hemolytic anemia due to red cell pyruvate kinase deficiency · score 0.04
delta-beta-thalassemia · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96HA8-F1	alphafold	PREDICTED	94.28	—

Amino-acid sequence (205 residues)

MEGNGPAAVH YQPASPPRDA CVYSSCYCEE NIWKLCEYIK NHDQYPLEEC YAVFISNERK MIPIWKQQAR PGDGPVIWDY HVVLLHVSSG GQNFIYDLDT VLPFPCLFDT YVEDAFKSDD DIHPQFRRKF RVIRADSYLK NFASDRSHMK DSSGNWREPP PPYPCIETGD SKMNLNDFIS MDPKVGWGAV YTLSEFTHRF GSKNC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards