About Coiled-coil domain-containing protein 120
Coiled-coil domain-containing protein 120 (CCDC120) is a protein
from Homo sapiens identified by UniProt accession
Q96HB5, 630 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Coiled-coil domain-containing protein 120 |
|---|
| UniProt accession | Q96HB5 |
|---|
| Gene | CCDC120 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 630 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (26)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- Short stature · score 0.11
- MODY · score 0.06
- attention deficit hyperactivity disorder · score 0.06
- Tourette syndrome · score 0.05
- schizophrenia 15 · score 0.05
- attention deficit-hyperactivity disorder 8 · score 0.05
- hyperproinsulinemia · score 0.05
- glycogen storage disorder due to hepatic glycogen synthase deficiency · score 0.05
- Glycogen storage disease due to hepatic glycogen synthase deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96HB5-F1 | alphafold | PREDICTED | 55.50 | — |
Amino-acid sequence (630 residues)
MEVKGQLISS PTFNAPAALF GEAAPQVKSE RLRGLLDRQR TLQEALSLKL QELRKVCLQE AELTGQLPPE CPLEPGERPQ LVRRRPPTAR AYPPPHPNQA HHSLCPAEEL ALEALEREVS VQQQIAAAAR RLALAPDLST EQRRRRRQVQ ADALRRLHEL EEQLRDVRAR LGLPVLPLPQ PLPLSTGSVI TTQGVCLGMR LAQLSQEDVV LHSESSSLSE SGASHDNEEP HGCFSLAERP SPPKAWDQLR AVSGGSPERR TPWKPPPSDL YGDLKSRRNS VASPTSPTRS LPRSASSFEG RSVPATPVLT RGAGPQLCKP EGLHSRQWSG SQDSQMGFPR ADPASDRASL FVARTRRSNS SEALLVDRAA GGGAGSPPAP LAPSASGPPV CKSSEVLYER PQPTPAFSSR TAGPPDPPRA ARPSSAAPAS RGAPRLPPVC GDFLLDYSLD RGLPRSGGGT GWGELPPAAE VPGPLSRRDG LLTMLPGPPP VYAADSNSPL LRTKDPHTRA TRTKPCGLPP EAAEGPEVHP NPLLWMPPPT RIPSAGERSG HKNLALEGLR DWYIRNSGLA AGPQRRPVLP SVGPPHPPFL HARCYEVGQA LYGAPSQAPL PHSRSFTAPP VSGRYGGCFY
Explore Coiled-coil domain-containing protein 120 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets