MORF4 family-associated protein 1-like 1 (MRFAP1L1)

About MORF4 family-associated protein 1-like 1

MORF4 family-associated protein 1-like 1 (MRFAP1L1) is a protein from Homo sapiens identified by UniProt accession Q96HT8, 127 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

Target properties

Protein name	MORF4 family-associated protein 1-like 1
UniProt accession	Q96HT8
Gene	MRFAP1L1
Organism	Homo sapiens
Length	127 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (16)

Diseases linked to this target (Open Targets).

mean platelet volume · score 0.11
FEV/FVC ratio · score 0.07
type 2 diabetes mellitus · score 0.03
blood protein measurement · score 0.02
Drugs used in diabetes use measurement · score 0.02
adolescent idiopathic scoliosis · score 0.02
Ataxia-telangiectasia · score 0.01
ovarian carcinoma · score 0.01
chronic kidney disease · score 0.01
Alzheimer disease · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96HT8-F1	alphafold	PREDICTED	82.79	—

Amino-acid sequence (127 residues)

MRPLDIDEVE APEEVEVLEP EEDFEQFLLP VINEMREDIA SLIREHGRAY LRTRSKLWEM DNMLIQIKTQ VEASEESALN HVQHPSGEAD ERVSELCEKA EEKAKEIAKM AEMLVELVWR IERSESS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards