Cytochrome c oxidase assembly protein COX14 (COX14)

About Cytochrome c oxidase assembly protein COX14

Cytochrome c oxidase assembly protein COX14 (COX14) is a protein from Homo sapiens identified by UniProt accession Q96I36, 57 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.

Target properties

Protein name	Cytochrome c oxidase assembly protein COX14
UniProt accession	Q96I36
Gene	COX14
Organism	Homo sapiens
Length	57 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (35)

Diseases linked to this target (Open Targets).

cytochrome-c oxidase deficiency disease · score 0.48
mitochondrial complex 4 deficiency, nuclear type 10 · score 0.47
Isolated cytochrome C oxidase deficiency · score 0.37
systolic blood pressure · score 0.17
lymphocyte count · score 0.16
hypertension · score 0.16
heel bone mineral density · score 0.14
diastolic blood pressure · score 0.12
peak expiratory flow · score 0.11
cardiovascular disease · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96I36-F1	alphafold	PREDICTED	85.70	—

Amino-acid sequence (57 residues)

MPTGKQLADI GYKTFSTSMM LLTVYGGYLC SVRVYHYFQW RRAQRQAAEE QKTSGIM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards