Transmembrane protein 141 (TMEM141)

About Transmembrane protein 141

Transmembrane protein 141 (TMEM141) is a protein from Homo sapiens identified by UniProt accession Q96I45, 108 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Transmembrane protein 141
UniProt accession	Q96I45
Gene	TMEM141
Organism	Homo sapiens
Length	108 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

Crohn's disease · score 0.01
hepatocellular carcinoma · score 0.01
Neurodevelopmental disorder · score 0.01
colorectal cancer · score 0.00
Sjogren syndrome · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96I45-F1	alphafold	PREDICTED	63.91	—

Amino-acid sequence (108 residues)

MVNLGLSRVD DAVAAKHPGL GEYAACQSHA FMKGVFTFVT GTGMAFGLQM FIQRKFPYPL QWSLLVAVVA GSVVSYGVTR VESEKCNNLW LFLETGQLPK DRSTDQRS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards