About LIM domain-containing protein ajuba
LIM domain-containing protein ajuba (AJUBA) is a protein
from Homo sapiens identified by UniProt accession
Q96IF1, 538 residues long.
MolForge cross-references it against 0 known binders and
98 disease associations.
Target properties
| Protein name | LIM domain-containing protein ajuba |
|---|
| UniProt accession | Q96IF1 |
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| Gene | AJUBA |
|---|
| Organism | Homo sapiens |
|---|
| Length | 538 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (98)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- head and neck squamous cell carcinoma · score 0.41
- breast adenocarcinoma · score 0.26
- clear cell renal carcinoma · score 0.25
- seborrheic keratosis · score 0.15
- mathematical ability · score 0.12
- neoplasm · score 0.09
- esophageal squamous cell carcinoma · score 0.09
- hepatocellular carcinoma · score 0.08
- macula measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96IF1-F1 | alphafold | PREDICTED | 56.96 | — |
Amino-acid sequence (538 residues)
MERLGEKASR LLEKFGRRKG ESSRSGSDGT PGPGKGRLSG LGGPRKSGPR GATGGPGDEP LEPAREQGSL DAERNQRGSF EAPRYEGSFP AGPPPTRALP LPQSLPPDFR LEPTAPALSP RSSFASSSAS DASKPSSPRG SLLLDGAGAG GAGGSRPCSN RTSGISMGYD QRHGSPLPAG PCLFGPPLAG APAGYSPGGV PSAYPELHAA LDRLYAQRPA GFGCQESRHS YPPALGSPGA LAGAGVGAAG PLERRGAQPG RHSVTGYGDC AVGARYQDEL TALLRLTVGT GGREAGARGE PSGIEPSGLE EPPGPFVPEA ARARMREPEA REDYFGTCIK CNKGIYGQSN ACQALDSLYH TQCFVCCSCG RTLRCKAFYS VNGSVYCEED YLFSGFQEAA EKCCVCGHLI LEKILQAMGK SYHPGCFRCI VCNKCLDGIP FTVDFSNQVY CVTDYHKNYA PKCAACGQPI LPSEGCEDIV RVISMDRDYH FECYHCEDCR MQLSDEEGCC CFPLDGHLLC HGCHMQRLNA RQPPANYI
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