About DISP complex protein LRCH3
DISP complex protein LRCH3 (LRCH3) is a protein
from Homo sapiens identified by UniProt accession
Q96II8, 777 residues long.
MolForge cross-references it against 0 known binders and
5 disease associations.
Target properties
| Protein name | DISP complex protein LRCH3 |
|---|
| UniProt accession | Q96II8 |
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| Gene | LRCH3 |
|---|
| Organism | Homo sapiens |
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| Length | 777 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (5)
Diseases linked to this target (Open Targets).
- basophil count · score 0.20
- Pallister-Hall syndrome · score 0.00
- cancer · score 0.00
- meningococcal infection · score 0.00
- bacterial disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96II8-F1 | alphafold | PREDICTED | 65.42 | — |
Amino-acid sequence (777 residues)
MAAAGLVAVA AAAEYSGTVA SGGNLPGVHC GPSSGAGPGF GPGSWSRSLD RALEEAAVTG VLSLSGRKLR EFPRGAANHD LTDTTRADLS RNRLSEIPIE ACHFVSLENL NLYQNCIRYI PEAILNLQAL TFLNISRNQL STLPVHLCNL PLKVLIASNN KLVSLPEEIG HLRHLMELDV SCNEIQTIPS QIGNLEALRD LNVRRNHLVH LPEELAELPL IRLDFSCNKI TTIPVCYRNL RHLQTITLDN NPLQSPPAQI CIKGKVHIFK YLNIQACKIA PDLPDYDRRP LGFGSCHEEL YSSRPYGALD SGFNSVDSGD KRWSGNEPTD EFSDLPLRVA EITKEQRLRR ESQYQENRGS LVVTNGGVEH DLDQIDYIDS CTAEEEEAEV RQPKGPDPDS LSSQFMAYIE QRRISHEGSP VKPVAIREFQ KTEDMRRYLH QNRVPAEPSS LLSLSASHNQ LSHTDLELHQ RREQLVERTR REAQLAALQY EEEKIRTKQI QRDAVLDFVK QKASQSPQKQ HPLLDGVDGE CPFPSRRSQH TDDSALCMSL SGLNQVGCAA TLPHSSAFTP LKSDDRPNAL LSSPATETVH HSPAYSFPAA IQRNQPQRPE SFLFRAGVRA ETNKGHASPL PPSAAPTTDS TDSITGQNSR QREEELELID QLRKHIEYRL KVSLPCDLGA ALTDGVVLCH LANHVRPRSV PSIHVPSPAV PKLTMAKCRR NVENFLEACR KIGVPQEQLC LPLHILEEKG LSQVAVTVQA LLELAPPKQQ QHQLSAV
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