Terminal nucleotidyltransferase 5A (TENT5A)

About Terminal nucleotidyltransferase 5A

Terminal nucleotidyltransferase 5A (TENT5A) is a protein from Homo sapiens identified by UniProt accession Q96IP4, 442 residues long. MolForge cross-references it against 0 known binders and 437 disease associations.

Target properties

Protein name	Terminal nucleotidyltransferase 5A
UniProt accession	Q96IP4
Gene	TENT5A
Organism	Homo sapiens
Length	442 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (437)

Diseases linked to this target (Open Targets).

body height · score 0.50
osteogenesis imperfecta · score 0.48
cystatin C measurement · score 0.45
neutrophil count · score 0.44
basophil count · score 0.43
monocyte percentage of leukocytes · score 0.42
refractive error measurement · score 0.42
monocyte count · score 0.41
BMI-adjusted waist-hip ratio · score 0.40
neutrophil percentage of leukocytes · score 0.40

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96IP4-F1	alphafold	PREDICTED	79.57	—

Amino-acid sequence (442 residues)

MAEGEGYFAM SEDELACSPY IPLGGDFGGG DFGGGDFGGG DFGGGGSFGG HCLDYCESPT AHCNVLNWEQ VQRLDGILSE TIPIHGRGNF PTLELQPSLI VKVVRRRLAE KRIGVRDVRL NGSAASHVLH QDSGLGYKDL DLIFCADLRG EGEFQTVKDV VLDCLLDFLP EGVNKEKITP LTLKEAYVQK MVKVCNDSDR WSLISLSNNS GKNVELKFVD SLRRQFEFSV DSFQIKLDSL LLFYECSENP MTETFHPTII GESVYGDFQE AFDHLCNKII ATRNPEEIRG GGLLKYCNLL VRGFRPASDE IKTLQRYMCS RFFIDFSDIG EQQRKLESYL QNHFVGLEDR KYEYLMTLHG VVNESTVCLM GHERRQTLNL ITMLAIRVLA DQNVIPNVAN VTCYYQPAPY VADANFSNYY IAQVQPVFTC QQQTYSTWLP CN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards