About V-set and immunoglobulin domain-containing protein 2
V-set and immunoglobulin domain-containing protein 2 (VSIG2) is a protein
from Homo sapiens identified by UniProt accession
Q96IQ7, 327 residues long.
MolForge cross-references it against 0 known binders and
47 disease associations.
Target properties
| Protein name | V-set and immunoglobulin domain-containing protein 2 |
|---|
| UniProt accession | Q96IQ7 |
|---|
| Gene | VSIG2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 327 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (47)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.34
- endothelial cell-selective adhesion molecule measurement · score 0.24
- schizophrenia · score 0.07
- autism spectrum disorder · score 0.06
- neoplasm · score 0.06
- obsessive-compulsive disorder · score 0.05
- bipolar disorder · score 0.05
- attention deficit hyperactivity disorder · score 0.05
- unipolar depression · score 0.05
- Tourette syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96IQ7-F1 | alphafold | PREDICTED | 80.18 | — |
Amino-acid sequence (327 residues)
MAELPGPFLC GALLGFLCLS GLAVEVKVPT EPLSTPLGKT AELTCTYSTS VGDSFALEWS FVQPGKPISE SHPILYFTNG HLYPTGSKSK RVSLLQNPPT VGVATLKLTD VHPSDTGTYL CQVNNPPDFY TNGLGLINLT VLVPPSNPLC SQSGQTSVGG STALRCSSSE GAPKPVYNWV RLGTFPTPSP GSMVQDEVSG QLILTNLSLT SSGTYRCVAT NQMGSASCEL TLSVTEPSQG RVAGALIGVL LGVLLLSVAA FCLVRFQKER GKKPKETYGG SDLREDAIAP GISEHTCMRA DSSKGFLERP SSASTVTTTK SKLPMVV
Explore V-set and immunoglobulin domain-containing protein 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets