Zinc finger protein 414 (ZNF414)

About Zinc finger protein 414

Zinc finger protein 414 (ZNF414) is a protein from Homo sapiens identified by UniProt accession Q96IQ9, 312 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Zinc finger protein 414
UniProt accession	Q96IQ9
Gene	ZNF414
Organism	Homo sapiens
Length	312 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

basophil count · score 0.21
basophil percentage of leukocytes · score 0.19
eosinophil percentage of leukocytes · score 0.16
lean body mass · score 0.10
eosinophil count · score 0.04
sporadic fetal brain disruption sequence · score 0.04
X-linked intellectual disability-plagiocephaly syndrome · score 0.04
high density lipoprotein cholesterol measurement · score 0.03
triglyceride measurement · score 0.02
cancer · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96IQ9-F1	alphafold	PREDICTED	59.90	—

Amino-acid sequence (312 residues)

MEEKPSGPIP DMLATAEPSS SETDKEVLSP AVPAAAPSSS MSEEPGPEQA ATPPVWERGG AGGMQQGSSP APDSCQPGPG PSPGLTSIVS GTSEDLRPPR RRPPPGKQIP CSSPGCCLSF PSVRDLAQHL RTHCPPTQSL EGKLFRCSAL SCTETFPSMQ ELVAHSKLHY KPNRYFKCEN CLLRFRTHRS LFKHLHVCAE HAQSPAPPPP PALDREPPAP ERPPEVDPAS APGLPFPLLE PFTTPAPAPT GPFLPYLNPA PFGLSPPRLR PFLAAAPGPP ASSAAVWKKS QGAGSSPRRP QGGSDAPSGA CR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards