About Serine/Arginine-related protein 53
Serine/Arginine-related protein 53 (RSRC1) is a protein
from Homo sapiens identified by UniProt accession
Q96IZ7, 334 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Serine/Arginine-related protein 53 |
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| UniProt accession | Q96IZ7 |
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| Gene | RSRC1 |
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| Organism | Homo sapiens |
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| Length | 334 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (68)
Diseases linked to this target (Open Targets).
- autosomal recessive non-syndromic intellectual disability · score 0.69
- genetic disorder · score 0.47
- body mass index · score 0.34
- unipolar depression · score 0.34
- body height · score 0.33
- schizophrenia · score 0.31
- bipolar disorder · score 0.31
- attention deficit hyperactivity disorder · score 0.31
- autism spectrum disorder · score 0.30
- smoking status measurement · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96IZ7-F1 | alphafold | PREDICTED | 58.44 | — |
Amino-acid sequence (334 residues)
MGRRSSDTEE ESRSKRKKKH RRRSSSSSSS DSRTYSRKKG GRKSRSKSRS WSRDLQPRSH SYDRRRRHRS SSSSSYGSRR KRSRSRSRGR GKSYRVQRSR SKSRTRRSRS RPRLRSHSRS SERSSHRRTR SRSRDRERRK GRDKEKREKE KDKGKDKELH NIKRGESGNI KAGLEHLPPA EQAKARLQLV LEAAAKADEA LKAKERNEEE AKRRKEEDQA TLVEQVKRVK EIEAIESDSF VQQTFRSSKE VKKSVEPSEV KQATSTSGPA SAVADPPSTE KEIDPTSIPT AIKYQDDNSL AHPNLFIEKA DAEEKWFKRL IALRQERLMG SPVA
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