CUGBP Elav-like family member 6 (CELF6)

About CUGBP Elav-like family member 6

CUGBP Elav-like family member 6 (CELF6) is a protein from Homo sapiens identified by UniProt accession Q96J87, 481 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	CUGBP Elav-like family member 6
UniProt accession	Q96J87
Gene	CELF6
Organism	Homo sapiens
Length	481 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.26
aspartate aminotransferase measurement · score 0.25
brain measurement · score 0.05
Paraganglioma · score 0.03
neoplasm · score 0.03
body height · score 0.03
triglyceride measurement · score 0.02
cancer · score 0.02
sitting height measurement · score 0.02
triple-negative breast cancer · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96J87-F1	alphafold	PREDICTED	67.71	—

Amino-acid sequence (481 residues)

MAAAPGGSAQ PAGPGPRLGF STADSGVGMS GLNPGPAVPM KDHDAIKLFV GQIPRGLDEQ DLKPLFEEFG RIYELTVLKD RLTGLHKGCA FLTYCARDSA LKAQSALHEQ KTLPGMNRPI QVKPAASEGR GEDRKLFVGM LGKQQGEEDV RRLFQPFGHI EECTVLRSPD GTSKGCAFVK FGSQGEAQAA IRGLHGSRTM AGASSSLVVK LADTDRERAL RRMQQMAGHL GAFHPAPLPL GACGAYTTAI LQHQAALLAA AQGPGLGPVA AVAAQMQHVA AFSLVAAPLL PAAAANSPPG SGPGTLPGLP APIGVNGFGP LTPQTNGQPG SDTLYNNGLS PYPAQSPGVA DPLQQAYAGM HHYAAAYPSA YAPVSTAFPQ QPSALPQQQR EGPEGCNLFI YHLPQEFGDA ELIQTFLPFG AVVSAKVFVD RATNQSKCFG FVSFDNPTSA QTAIQAMNGF QIGMKRLKVQ LKRPKDANRP Y

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards