About Lysyl oxidase homolog 4
Lysyl oxidase homolog 4 (LOXL4) is a protein
from Homo sapiens identified by UniProt accession
Q96JB6, 756 residues long.
MolForge cross-references it against 0 known binders and
100 disease associations.
Target properties
| Protein name | Lysyl oxidase homolog 4 |
|---|
| UniProt accession | Q96JB6 |
|---|
| Gene | LOXL4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 756 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (3)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (100)
Diseases linked to this target (Open Targets).
- pulse pressure measurement · score 0.41
- body height · score 0.39
- body mass index · score 0.34
- breast adenocarcinoma · score 0.23
- lung adenocarcinoma · score 0.19
- cutaneous melanoma · score 0.18
- metabolite measurement · score 0.14
- endometrial cancer · score 0.14
- neoplasm · score 0.11
- hepatocellular carcinoma · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96JB6-F1 | alphafold | PREDICTED | 86.41 | — |
Amino-acid sequence (756 residues)
MAWSPPATLF LFLLLLGQPP PSRPQSLGTT KLRLVGPESK PEEGRLEVLH QGQWGTVCDD NFAIQEATVA CRQLGFEAAL TWAHSAKYGQ GEGPIWLDNV RCVGTESSLD QCGSNGWGVS DCSHSEDVGV ICHPRRHRGY LSETVSNALG PQGRRLEEVR LKPILASAKQ HSPVTEGAVE VKYEGHWRQV CDQGWTMNNS RVVCGMLGFP SEVPVDSHYY RKVWDLKMRD PKSRLKSLTN KNSFWIHQVT CLGTEPHMAN CQVQVAPARG KLRPACPGGM HAVVSCVAGP HFRPPKTKPQ RKGSWAEEPR VRLRSGAQVG EGRVEVLMNR QWGTVCDHRW NLISASVVCR QLGFGSAREA LFGARLGQGL GPIHLSEVRC RGYERTLSDC PALEGSQNGC QHENDAAVRC NVPNMGFQNQ VRLAGGRIPE EGLLEVQVEV NGVPRWGSVC SENWGLTEAM VACRQLGLGF AIHAYKETWF WSGTPRAQEV VMSGVRCSGT ELALQQCQRH GPVHCSHGGG RFLAGVSCMD SAPDLVMNAQ LVQETAYLED RPLSQLYCAH EENCLSKSAD HMDWPYGYRR LLRFSTQIYN LGRTDFRPKT GRDSWVWHQC HRHYHSIEVF THYDLLTLNG SKVAEGHKAS FCLEDTNCPT GLQRRYACAN FGEQGVTVGC WDTYRHDIDC QWVDITDVGP GNYIFQVIVN PHYEVAESDF SNNMLQCRCK YDGHRVWLHN CHTGNSYPAN AELSLEQEQR LRNNLI
Explore Lysyl oxidase homolog 4 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets