Zinc finger protein 479 (ZNF479)

About Zinc finger protein 479

Zinc finger protein 479 (ZNF479) is a protein from Homo sapiens identified by UniProt accession Q96JC4, 524 residues long. MolForge cross-references it against 0 known binders and 98 disease associations.

Target properties

Protein name	Zinc finger protein 479
UniProt accession	Q96JC4
Gene	ZNF479
Organism	Homo sapiens
Length	524 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (98)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.29
hepatocellular carcinoma · score 0.20
lung adenocarcinoma · score 0.19
gastric carcinoma · score 0.18
oral squamous cell carcinoma · score 0.18
T-cell acute lymphoblastic leukemia · score 0.18
chronic lymphocytic leukemia · score 0.18
breast carcinoma · score 0.18
acute myeloid leukemia · score 0.18
head and neck squamous cell carcinoma · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96JC4-F1	alphafold	PREDICTED	74.26	—

Amino-acid sequence (524 residues)

MAKRPGPPGS REMGLLTFRD IAIEFSLEEW QCLDCAQRNL YRDVMLENYR NLVSLGIAVS KPDLITCLEQ NKESQNIKRN EMVAKHPVTR SHFTQDLQPE QGIKDSLQKV IPRTYGKCGH EKLQFKKCCK SVGEYEVHKG GYSEVNQCLS TTQNKIFQTH KYVKVFGKFS NSNRDKTRYT GNKHFKCNKY GKSFCMLSHL NQHQVIHTRE KSYKCKECGK SFNCSSNHTT HKIIHTGEKP YRCEECGKAF SWSANLTRHK RTHTGEKPYT CEECGQAFRR SSALTNHKRI HTGERPYKCE ECGKAFSVSS TLTDHKRIHT GEKPCRCEEC GKAFSWSSNL TRHKRIHTRE KPYACEECGQ AFSLSSNLMR HRRIHTGEKP YTCEECGQDF RRSSALTIHK RIHTGERPYK CEECGKVFSL SSTLTDHKRI HTGERPYKCE ECGKAFSLSS TLTDHKRIHT GERPYTCEEC GKAFNCSSTL MQHKRIHTGE KPYKCEECEQ AFKWHSSLAK HKIIHTGEKP YKCE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards