Transcription factor BTF3 homolog 4 (BTF3L4)

Homo sapiens — UniProt Q96K17

Gene: BTF3L4Homo sapiensSwissProt reviewed

About Transcription factor BTF3 homolog 4

Transcription factor BTF3 homolog 4 (BTF3L4) is a protein from Homo sapiens identified by UniProt accession Q96K17, 158 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein nameTranscription factor BTF3 homolog 4
UniProt accessionQ96K17
GeneBTF3L4
OrganismHomo sapiens
Length158 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (8)

Diseases linked to this target (Open Targets).

  • acute myeloid leukemia · score 0.02
  • colorectal cancer · score 0.01
  • neoplasm · score 0.00
  • Alzheimer disease · score 0.00
  • myeloid sarcoma · score 0.00
  • axial length measurement · score 0.00
  • Amyotrophic lateral sclerosis · score 0.00
  • cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q96K17-F1alphafoldPREDICTED78.12—

Amino-acid sequence (158 residues)

MNQEKLAKLQ AQVRIGGKGT ARRKKKVVHR TATADDKKLQ SSLKKLAVNN IAGIEEVNMI KDDGTVIHFN NPKVQASLSA NTFAITGHAE AKPITEMLPG ILSQLGADSL TSLRKLAEQF PRQVLDSKAP KPEDIDEEDD DVPDLVENFD EASKNEAN

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Quick facts

UniProtQ96K17
GeneBTF3L4
OrganismHomo sapiens
Length158
Binders0
Diseases8
View on UniProt