About RBPJ-interacting and tubulin-associated protein 1
RBPJ-interacting and tubulin-associated protein 1 (RITA1) is a protein
from Homo sapiens identified by UniProt accession
Q96K30, 269 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | RBPJ-interacting and tubulin-associated protein 1 |
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| UniProt accession | Q96K30 |
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| Gene | RITA1 |
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| Organism | Homo sapiens |
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| Length | 269 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- body mass index · score 0.08
- breast cancer · score 0.04
- platelet count · score 0.03
- hepatocellular carcinoma · score 0.01
- psoriasis · score 0.01
- IGA glomerulonephritis · score 0.00
- myelodysplastic syndrome · score 0.00
- urinary bladder carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96K30-F1 | alphafold | PREDICTED | 59.34 | — |
Amino-acid sequence (269 residues)
MKTPVELAVS GMQTLGLQHR CRGGYRVKAR TSYVDETLFG SPAGTRPTPP DFDPPWVEKA NRTRGVGKEA SKALGAKGSC ETTPSRGSTP TLTPRKKNKY RPISHTPSYC DESLFGSRSE GASFGAPRMA KGDAAKLRAL LWTPPPTPRG SHSPRPREAP LRAIHPAGPS KTEPGPAADS QKLSMGGLHS SRPLKRGLSH SLTHLNVPST GHPATSAPHT NGPQDLRPST SGVTFRSPLV TSRARSVSIS VPSTPRRGGA TQKPKPPWK
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