Solute carrier family 35 member E1 (SLC35E1)

About Solute carrier family 35 member E1

Solute carrier family 35 member E1 (SLC35E1) is a protein from Homo sapiens identified by UniProt accession Q96K37, 410 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Solute carrier family 35 member E1
UniProt accession	Q96K37
Gene	SLC35E1
Organism	Homo sapiens
Length	410 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

neutrophil-to-lymphocyte ratio · score 0.16
leukocyte count · score 0.07
psoriasis · score 0.06
self reported educational attainment · score 0.05
schizophrenia · score 0.04
intelligence · score 0.04
hemochromatosis type 5 · score 0.03
FTH1-related iron overload · score 0.03
osteosarcoma · score 0.02
Plasmodium falciparum malaria · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96K37-F1	alphafold	PREDICTED	74.91	—

Amino-acid sequence (410 residues)

MAAAAVGAGH GAGGPGAASS SGGAREGARV AALCLLWYAL SAGGNVVNKV ILSAFPFPVT VSLCHILALC AGLPPLLRAW RVPPAPPVSG PGPSPHPSSG PLLPPRFYPR YVLPLAFGKY FASVSAHVSI WKVPVSYAHT VKATMPIWVV LLSRIIMKEK QSTKVYLSLI PIISGVLLAT VTELSFDMWG LVSALAATLC FSLQNIFSKK VLRDSRIHHL RLLNILGCHA VFFMIPTWVL VDLSAFLVSS DLTYVYQWPW TLLLLAVSGF CNFAQNVIAF SILNLVSPLS YSVANATKRI MVITVSLIML RNPVTSTNVL GMMTAILGVF LYNKTKYDAN QQARKHLLPV TTADLSSKER HRSPLEKPHN GLLFPQHGDY QYGRNNILTD HFQYSRQSYP NSYSLNRYDV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards