Beta-Ala-His dipeptidase (CNDP1)

About Beta-Ala-His dipeptidase

Beta-Ala-His dipeptidase (CNDP1) is a protein from Homo sapiens identified by UniProt accession Q96KN2, 507 residues long. MolForge cross-references it against 0 known binders and 115 disease associations.

Target properties

Protein name	Beta-Ala-His dipeptidase
UniProt accession	Q96KN2
Gene	CNDP1
Organism	Homo sapiens
Length	507 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (115)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.48
neurodegenerative disease · score 0.37
beta-Ala-His dipeptidase measurement · score 0.32
hepatocellular carcinoma · score 0.10
liver dysplastic nodule · score 0.08
cancer · score 0.08
metabolite measurement · score 0.08
body height · score 0.08
diabetic nephropathy · score 0.07
Barrett's esophagus · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96KN2-F1	alphafold	PREDICTED	93.98	—

Amino-acid sequence (507 residues)

MDPKLGRMAA SLLAVLLLLL ERGMFSSPSP PPALLEKVFQ YIDLHQDEFV QTLKEWVAIE SDSVQPVPRF RQELFRMMAV AADTLQRLGA RVASVDMGPQ QLPDGQSLPI PPVILAELGS DPTKGTVCFY GHLDVQPADR GDGWLTDPYV LTEVDGKLYG RGATDNKGPV LAWINAVSAF RALEQDLPVN IKFIIEGMEE AGSVALEELV EKEKDRFFSG VDYIVISDNL WISQRKPAIT YGTRGNSYFM VEVKCRDQDF HSGTFGGILH EPMADLVALL GSLVDSSGHI LVPGIYDEVV PLTEEEINTY KAIHLDLEEY RNSSRVEKFL FDTKEEILMH LWRYPSLSIH GIEGAFDEPG TKTVIPGRVI GKFSIRLVPH MNVSAVEKQV TRHLEDVFSK RNSSNKMVVS MTLGLHPWIA NIDDTQYLAA KRAIRTVFGT EPDMIRDGST IPIAKMFQEI VHKSVVLIPL GAVDDGEHSQ NEKINRWNYI EGTKLFAAFF LEMAQLH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards