Cytosolic non-specific dipeptidase (CNDP2)

About Cytosolic non-specific dipeptidase

Cytosolic non-specific dipeptidase (CNDP2) is a protein from Homo sapiens identified by UniProt accession Q96KP4, 475 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.

Target properties

Protein name	Cytosolic non-specific dipeptidase
UniProt accession	Q96KP4
Gene	CNDP2
Organism	Homo sapiens
Length	475 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (72)

Diseases linked to this target (Open Targets).

serum metabolite measurement · score 0.45
refractive error · score 0.39
body height · score 0.31
Abnormality of refraction · score 0.31
refractive error measurement · score 0.29
glioblastoma multiforme · score 0.16
mean corpuscular volume · score 0.13
metabolite measurement · score 0.09
blood protein measurement · score 0.05
Hepatic veno-occlusive disease - immunodeficiency · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96KP4-F1	alphafold	PREDICTED	97.78	—

Amino-acid sequence (475 residues)

MAALTTLFKY IDENQDRYIK KLAKWVAIQS VSAWPEKRGE IRRMMEVAAA DVKQLGGSVE LVDIGKQKLP DGSEIPLPPI LLGRLGSDPQ KKTVCIYGHL DVQPAALEDG WDSEPFTLVE RDGKLYGRGS TDDKGPVAGW INALEAYQKT GQEIPVNVRF CLEGMEESGS EGLDELIFAR KDTFFKDVDY VCISDNYWLG KKKPCITYGL RGICYFFIEV ECSNKDLHSG VYGGSVHEAM TDLILLMGSL VDKRGNILIP GINEAVAAVT EEEHKLYDDI DFDIEEFAKD VGAQILLHSH KKDILMHRWR YPSLSLHGIE GAFSGSGAKT VIPRKVVGKF SIRLVPNMTP EVVGEQVTSY LTKKFAELRS PNEFKVYMGH GGKPWVSDFS HPHYLAGRRA MKTVFGVEPD LTREGGSIPV TLTFQEATGK NVMLLPVGSA DDGAHSQNEK LNRYNYIEGT KMLAAYLYEV SQLKD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards