About POM121-like protein 2
POM121-like protein 2 (POM121L2) is a protein
from Homo sapiens identified by UniProt accession
Q96KW2, 1035 residues long.
MolForge cross-references it against 0 known binders and
82 disease associations.
Target properties
| Protein name | POM121-like protein 2 |
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| UniProt accession | Q96KW2 |
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| Gene | POM121L2 |
|---|
| Organism | Homo sapiens |
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| Length | 1035 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (82)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.45
- mean corpuscular hemoglobin · score 0.37
- mathematical ability · score 0.35
- diet measurement · score 0.33
- self reported educational attainment · score 0.31
- chronic obstructive pulmonary disease · score 0.30
- smoking status measurement · score 0.24
- cognitive function measurement · score 0.24
- excessive daytime sleepiness measurement · score 0.19
- mean corpuscular volume · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96KW2-F1 | alphafold | PREDICTED | 41.41 | — |
Amino-acid sequence (1035 residues)
MGSFLSKLEL SPSSPAQVRT DLPERPTKRR PPQPLHQVHR VQFVHRAHPA PRYRPVRRRP NLDPANPTTW LANEAWRRFP MKKSQNSPLG PLPSDWWESY LKRTIWSLRH PRPIWSPVTI RITPPDQRVP PSTSPEDVIA LAGLPPSEEL ADPCSKETVL RALRECRKGK GRLEEPLFPE SLDSKRRSPE TRPSAFKPLM KNGTLTSFVP RPGPLKRSLH SWGSDHSLTK RPNCSSMSSL ASIYRGGTLS SKRNAIGSSY SSCRNFSDPW KRSVPSVSFE TPEWPIKKEK SCHRPSSPVP LVSDFESLGG SESSGQQNQK IPQLPSSPEN LVSEIPPPQL GYAVSDENLT LGKKAELQVS NNAGEDTTEV NTDPFPETWL AIQPSLSLAL PSSETDLTQG ANPQLENLRK MQKSLGPLAS PQSTGEATSV AHSPLKTPSL PTPPGCSQSE LLPGTSPDSK PTATFILLTP TSPTLPVTDT TWPPSTSQAD RSPMPPDPPA PPTIQSTLLG MVSSPTSHLS ASAPPDATSA HLMLKPILGP LHNSEIGSSS YSRISVTAAA SSISSLSTIQ GTLTPTFKPI FGSIDPLKTT PMIAPFSSKQ TPPPFTHAST HHFHGLVKAT SVVMSTTLAS TSKDSVFKPP LDFGVVNVTS AVGNTYSVPS TCDTFLLGTA QAFRADFTPA TGFIFPPHHH PTIPTVHTVT MFTQVLSSVV QISPRSSTAN FRGMGSPLPA SALVSTNWLA STPSISNLTP AITSPLGSSS RPPFPLSQGA NPQPAFGATN GQKQGPSQPA LMPSVSSSFL FGSSAVALPT PMPTPAQPAF ISTTQSALGC LTPSASTSQT PASTWSGIGG IPAGFPISQA STTGFRIVIQ THQSGAFGSV FGSRAPQPFT FGGFVTPMDC DESGIIMTGP DMSPTSGAFS IGALPSGTTN TMIPFGKGWS QNTEGLPSHR TAFSLGRGSI SARKTMAPIA QNTPVPGQAK AGSSVGFGMP FPPAQGSVGR GPFRSSASSF SIGAKSKTPK NREKGHSRRH HAYKK
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