Spermatogenesis-associated protein 17 (SPATA17)

About Spermatogenesis-associated protein 17

Spermatogenesis-associated protein 17 (SPATA17) is a protein from Homo sapiens identified by UniProt accession Q96L03, 361 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Spermatogenesis-associated protein 17
UniProt accession	Q96L03
Gene	SPATA17
Organism	Homo sapiens
Length	361 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (40)

Diseases linked to this target (Open Targets).

body height · score 0.38
lean body mass · score 0.35
appendicular lean mass · score 0.35
body weight · score 0.35
bone density · score 0.32
urate measurement · score 0.32
metabolite measurement · score 0.29
fat body mass · score 0.26
whole body water mass · score 0.21
base metabolic rate measurement · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96L03-F1	alphafold	PREDICTED	81.60	—

Amino-acid sequence (361 residues)

MATLARLQAR SSTVGNQYYF RNSVVDPFRK KENDAAVKIQ SWFRGCQVRA YIRHLNRIVT IIQKWWRSFL GRKQYQLTVQ VAYYTMMMNL YNAMAVRIQR RWRGYRVRKY LFNYYYLKEY LKVVSETNDA IRKALEEFAE MKEREEKKAN LEREEKKRDY QARKMHYLLS TKQIPGIYNS PFRKEPDPWE LQLQKAKPLT HRRPKVKQKD STSLTDWLAC TSARSFPRSE ILPPINRKQC QGPFRDITEV LEQRYRPLEP TLRVAEPIDE LKLAREELRR EEWLQNVNDN MFLPFSSYHK NEKYIPSMHL SSKYGPISYK EQFRSENPKK WICDKDFQTV LPSFELFSKY GKLYSKAGQI V

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards