About Sushi domain-containing protein 3
Sushi domain-containing protein 3 (SUSD3) is a protein
from Homo sapiens identified by UniProt accession
Q96L08, 255 residues long.
MolForge cross-references it against 0 known binders and
40 disease associations.
Target properties
| Protein name | Sushi domain-containing protein 3 |
|---|
| UniProt accession | Q96L08 |
|---|
| Gene | SUSD3 |
|---|
| Organism | Homo sapiens |
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| Length | 255 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (40)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.32
- neurodegenerative disease · score 0.31
- platelet crit · score 0.18
- serum gamma-glutamyl transferase measurement · score 0.11
- platelet component distribution width · score 0.09
- basophil count · score 0.05
- emotional symptom measurement · score 0.04
- acute myeloid leukemia · score 0.04
- neutrophil count · score 0.04
- breast cancer · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96L08-F1 | alphafold | PREDICTED | 69.07 | — |
Amino-acid sequence (255 residues)
MRWAAATLRG KARPRGRAGV TTPAPGNRTG TCAKLRLPPQ ATFQVLRGNG ASVGTVLMFR CPSNHQMVGS GLLTCTWKGS IAEWSSGSPV CKLVPPHETF GFKVAVIASI VSCAIILLMS MAFLTCCLLK CVKKSKRRRS NRSAQLWSQL KDEDLETVQA AYLGLKHFNK PVSGPSQAHD NHSFTTDHGE STSKLASVTR SVDKDPGIPR ALSLSGSSSS PQAQVMVHMA NPRQPLPASG LATGMPQQPA AYALG
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