About Sperm-egg fusion protein LLCFC1
Sperm-egg fusion protein LLCFC1 (LLCFC1) is a protein
from Homo sapiens identified by UniProt accession
Q96L11, 122 residues long.
MolForge cross-references it against 0 known binders and
80 disease associations.
Target properties
| Protein name | Sperm-egg fusion protein LLCFC1 |
|---|
| UniProt accession | Q96L11 |
|---|
| Gene | LLCFC1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 122 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (80)
Diseases linked to this target (Open Targets).
- reticulocyte measurement · score 0.13
- reticulocyte count · score 0.12
- Male infertility with spermatogenesis disorder due to single gene mutation · score 0.10
- azoospermia · score 0.09
- Female infertility due to fertilization defect · score 0.08
- Rare genetic female infertility · score 0.08
- partial chromosome Y deletion · score 0.08
- spermatogenic failure 3 · score 0.08
- spermatogenic failure 55 · score 0.08
- male infertility with teratozoospermia due to single gene mutation · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96L11-F1 | alphafold | PREDICTED | 60.83 | — |
Amino-acid sequence (122 residues)
MPPLAPQLCR AVFLVPILLL LQVKPLNGSP GPKDGSQTEK TPSADQNQEQ FEEHFVASSV GEMWQVVDMA QQEEDQSSKT AAVHKHSFHL SFCFSLASVM VFSGGPLRRT FPNIQLCFML TH
Explore Sperm-egg fusion protein LLCFC1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets