About Ecto-ADP-ribosyltransferase 5
Ecto-ADP-ribosyltransferase 5 (ART5) is a protein
from Homo sapiens identified by UniProt accession
Q96L15, 291 residues long.
MolForge cross-references it against 0 known binders and
10 disease associations.
Target properties
| Protein name | Ecto-ADP-ribosyltransferase 5 |
|---|
| UniProt accession | Q96L15 |
|---|
| Gene | ART5 |
|---|
| Organism | Homo sapiens |
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| Length | 291 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (10)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- visual perception measurement · score 0.23
- hemoglobin measurement · score 0.03
- blood protein measurement · score 0.02
- waist circumference · score 0.02
- adenoma · score 0.01
- parathyroid adenoma · score 0.01
- reading · score 0.00
- malaria · score 0.00
- hepatocellular carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96L15-F1 | alphafold | PREDICTED | 88.54 | — |
Amino-acid sequence (291 residues)
MALAALMIAL GSLGLHTWQA QAVPILPLGL APDTFDDTYV GCAEEMEEKA APLLKEEMAH HALLRESWEA AQETWEDKRR GLTLPPGFKA QNGIAIMVYT NSSNTLYWEL NQAVRTGGGS RELYMRHFPF KALHFYLIRA LQLLRGSGGC SRGPGEVVFR GVGSLRFEPK RLGDSVRLGQ FASSSLDKAV AHRFGNATLF SLTTCFGAPI QAFSVFPKER EVLIPPHEVF LVTRFSQDGA QSLVTLWSYN QTCSHFNCAY LGGEKRRGCV SAPGALGTGD LHMTKRHLQQ P
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