About Sorting nexin-22
Sorting nexin-22 (SNX22) is a protein
from Homo sapiens identified by UniProt accession
Q96L94, 193 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | Sorting nexin-22 |
|---|
| UniProt accession | Q96L94 |
|---|
| Gene | SNX22 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 193 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- osteogenesis imperfecta · score 0.52
- mean corpuscular volume · score 0.19
- erythrocyte count · score 0.19
- genetic disorder · score 0.16
- coronary artery disease · score 0.15
- apolipoprotein B measurement · score 0.14
- hemoglobin measurement · score 0.14
- mean platelet volume · score 0.14
- monocyte percentage of leukocytes · score 0.13
- low density lipoprotein cholesterol measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q96L94-F1 | alphafold | PREDICTED | 71.89 | — |
Amino-acid sequence (193 residues)
MLEVHIPSVG PEAEGPRQSP EKSHMVFRVE VLCSGRRHTV PRRYSEFHAL HKRIKKLYKV PDFPSKRLPN WRTRGLEQRR QGLEAYIQGI LYLNQEVPKE LLEFLRLRHF PTDPKASNWG TLREFLPGDS SSQQHQRPVL SFHVDPYVCN PSPESLPNVV VNGVLQGLYS FSISPDKAQP KAACHPAPLP PMP
Explore Sorting nexin-22 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets