Mas-related G-protein coupled receptor member X2 (MRGPRX2)

About Mas-related G-protein coupled receptor member X2

Mas-related G-protein coupled receptor member X2 (MRGPRX2) is a protein from Homo sapiens identified by UniProt accession Q96LB1, 330 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.

Target properties

Protein name	Mas-related G-protein coupled receptor member X2
UniProt accession	Q96LB1
Gene	MRGPRX2
Organism	Homo sapiens
Length	330 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96LB1-F1	alphafold	PREDICTED	81.70	—

Amino-acid sequence (330 residues)

MDPTTPAWGT ESTTVNGNDQ ALLLLCGKET LIPVFLILFI ALVGLVGNGF VLWLLGFRMR RNAFSVYVLS LAGADFLFLC FQIINCLVYL SNFFCSISIN FPSFFTTVMT CAYLAGLSML STVSTERCLS VLWPIWYRCR RPRHLSAVVC VLLWALSLLL SILEGKFCGF LFSDGDSGWC QTFDFITAAW LIFLFMVLCG SSLALLVRIL CGSRGLPLTR LYLTILLTVL VFLLCGLPFG IQWFLILWIW KDSDVLFCHI HPVSVVLSSL NSSANPIIYF FVGSFRKQWR LQQPILKLAL QRALQDIAEV DHSEGCFRQG TPEMSRSSLV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards