Uncharacterized protein CXorf58 (CXorf58)

About Uncharacterized protein CXorf58

Uncharacterized protein CXorf58 (CXorf58) is a protein from Homo sapiens identified by UniProt accession Q96LI9, 332 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Uncharacterized protein CXorf58
UniProt accession	Q96LI9
Gene	CXorf58
Organism	Homo sapiens
Length	332 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

concentration of large VLDL particles measurement · score 0.14
total lipids in large VLDL · score 0.13
phospholipids in medium VLDL measurement · score 0.13
concentration of small VLDL particles · score 0.11
total lipids in small VLDL · score 0.10
phospholipids in large VLDL measurement · score 0.10
cholesterol in large VLDL measurement · score 0.10
cholesterol in very large VLDL measurement · score 0.10
free cholesterol in large VLDL measurement · score 0.10
triglycerides in VLDL measurement · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96LI9-F1	alphafold	PREDICTED	76.12	—

Amino-acid sequence (332 residues)

MNRSSNVPRK GILKSGTRSL QKVRRVHFAN ARNARSLLSM LKDISAQIIQ RAWLSHTNKM IFRLLKHAIC AAEFYVTHEI LKKVAPLEAK LIKDPTMQCK IRFRFRGETF PPFIVFKIFL HTDGHGYKYF SGKNVLMPSS KAVDDACKLM GERKFHRIIM EDERIFPKSK VTDIMDVVTM QDYVQYRSFF DEAPAFSGGR NNSWRKLNLE NIPRTMLMYD IVHYSESGVI SNRLRNEMKF LLQRPVTQEI HKHQLRIVSE IRGPYLTVQP LYRPYKQQNQ VKFLGRRSKQ AQMKVEKMRK VYLAKEKNTS EVTEPKTGPS GTKDNYHLHS IF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards