DnaJ homolog subfamily C member 30, mitochondrial (DNAJC30)

About DnaJ homolog subfamily C member 30, mitochondrial

DnaJ homolog subfamily C member 30, mitochondrial (DNAJC30) is a protein from Homo sapiens identified by UniProt accession Q96LL9, 226 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	DnaJ homolog subfamily C member 30, mitochondrial
UniProt accession	Q96LL9
Gene	DNAJC30
Organism	Homo sapiens
Length	226 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (40)

Diseases linked to this target (Open Targets).

Leber hereditary optic neuropathy · score 0.46
Leber hereditary optic neuropathy, autosomal recessive · score 0.42
body height · score 0.18
IGF-1 measurement · score 0.09
appendicular lean mass · score 0.08
MODY · score 0.07
diabetes mellitus, permanent neonatal 4 · score 0.05
sex hormone-binding globulin measurement · score 0.05
triglyceride measurement · score 0.05
diabetes mellitus, transient neonatal, 3 · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q96LL9-F1	alphafold	PREDICTED	71.42	—

Amino-acid sequence (226 residues)

MAAMRWRWWQ RLLPWRLLQA RGFPQNSAPS LGLGARTYSQ GDCSYSRTAL YDLLGVPSTA TQAQIKAAYY RQCFLYHPDR NSGSAEAAER FTRISQAYVV LGSATLRRKY DRGLLSDEDL RGPGVRPSRT PAPDPGSPRT PPPTSRTHDG SRASPGANRT MFNFDAFYQA HYGEQLERER RLRARREALR KRQEYRSMKG LRWEDTRDTA AIFLIFSIFI IIGFYI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards